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High-Protein Spinach and Artichoke Chicken Casserole Recipe

4.8 from 128 reviews

This High-Protein Spinach and Artichoke Chicken Casserole is a creamy, cheesy, and nutritious dish that combines shredded chicken, fresh spinach, and artichoke hearts in a flavorful Greek yogurt and cream cheese base. Baked to golden perfection, it’s a perfect healthy comfort food packed with protein and great for a family dinner or meal prep.

Ingredients

Scale

Chicken and Vegetables

  • 2 large boneless, skinless chicken breasts (about 1 lb), cooked and shredded
  • 3 cups fresh baby spinach
  • 1 can (14 oz) artichoke hearts, drained and chopped

Dairy and Seasonings

  • 1 cup non-fat Greek yogurt
  • 1/2 cup light cream cheese, softened
  • 3/4 cup shredded mozzarella cheese
  • 1/4 cup grated Parmesan cheese
  • 2 cloves garlic, minced
  • 1/2 teaspoon salt
  • 1/4 teaspoon ground black pepper

Instructions

  1. Preheat Oven: Preheat your oven to 375°F (190°C) and grease a medium casserole dish with nonstick spray to prevent sticking and ensure easy cleanup.
  2. Make the Sauce: In a large bowl, combine the non-fat Greek yogurt, softened cream cheese, minced garlic, salt, and ground black pepper. Mix thoroughly until you achieve a smooth and creamy consistency without lumps.
  3. Combine Ingredients: Fold the shredded cooked chicken, fresh baby spinach, chopped artichoke hearts, and half of the shredded mozzarella cheese into the yogurt and cream cheese mixture, ensuring everything is evenly distributed.
  4. Assemble Casserole: Transfer the combined mixture into the prepared casserole dish. Evenly sprinkle the remaining mozzarella cheese and the grated Parmesan cheese on top to create a delicious cheesy crust when baked.
  5. Bake: Place the casserole in the preheated oven and bake for 30-35 minutes, or until the casserole is hot throughout, bubbly, and the cheese on top has melted and turned golden brown.
  6. Cool and Serve: Remove the casserole from the oven and let it cool for about 5 minutes before serving. This step helps the casserole set slightly for easier portioning and eating.

Notes

  • You can substitute fresh spinach with frozen spinach, but make sure to thaw and drain excess water before using.
  • Leftover casserole can be stored in an airtight container in the refrigerator for up to 3 days.
  • For an extra kick of flavor, consider adding red pepper flakes or your favorite herbs like oregano or thyme.
  • This recipe works well for meal prep and can be reheated in the microwave or oven.
  • If preferred, you may swap light cream cheese with regular cream cheese or sour cream for a richer texture.

Keywords: high-protein casserole, spinach chicken casserole, artichoke chicken bake, healthy chicken casserole, baked chicken dish, Greek yogurt casserole